Antiestrogens are designed to antagonize hormone induced proliferation and ERalpha target gene expression in mammary tumor cells.Commonly used drugs such as OH-Tamoxifen and ICI 182780 (Fulvestrant) block cell cycle progression in G0/G1.Inversely, the effect of cell cycle stage on ER regulated gene expression has not been OXYDANT CREME 3.75% / 12.5
During the first half of 2022, the World Health Organization reported an outbreak of acute severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from the United Kingdom (UK) where a cluster of cases Retail and Online was first observed in previously well children aged <6 years.Sporadic cases were then reported a
Abstract Background Across the Metazoa, similar genetic programs are found in the development of analogous, independently evolved, morphological features.The functional significance of this reuse and the underlying mechanisms of co-option remain unclear.Cephalopods have evolved a highly acute visual system with a cup-shaped retina and a novel refra
Background: Given increasing class sizes and desires to keep costs down, many medical GSPOT schools are developing regional clinical campuses.We found our regional campus system to be very successful in allowing class size expansion, inspiring a workforce for the state, and concurrently allowing our students to individualize their experience.We des
Whooping cough and diphtheria are vaccine preventable diseases.Diphtheria, due to Corynebacterium diphtheriae or Corynebactium ulcerans, two Gram positive bacteria, is a serious upper respiratory tract disease with high morbidity and mortality rates.Vaccination, via an acellular vaccine composed only of purified, detoxified diphtheria toxin, has si